Perfluoroalkyl substances (PFASs) show variable liver-to-blood ratios, with PFOA reaching a ratio of 0.32, indicating differential distribution based on chain length and isomer type.
Per- and polyfluoroalkyl substances research
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An increase in PFAS exposure over 10 years is linked to lower odds of metabolic syndrome and abdominal obesity in Taiwanese adolescents and young adults.
Extreme gradient boosting (XGBoost) achieved high accuracy with R2 values of 0.83 and 0.86 in predicting PFAS soil-water partition coefficients using 10 descriptors.
PFAS exposure is linked to altered innate immune biomarkers in bald eagle nestlings, with significant negative associations between some long-chain PFAS and complement-mediated lysis.
Facet-specific adsorption of PFOS and 6:2 Cl-PFESA onto hematite surfaces is supported by DFT calculations showing the (012) facet has the highest affinity.
Dietary PFOA exposure worsens colitis severity by promoting neutrophil infiltration, epithelial barrier disruption, and microbiome alterations in a DSS-induced colitis model.
- 1 cites
Aqueous PFOS exposure decouples gaseous carbon loss from mineral-associated carbon retention in wetland mesocosms.
Decabromodiphenyl ethane (DBDPE) promotes cancer-like traits in human breast cells and zebrafish xenografts, indicating potential health risks of this flame retardant.
Genetically predicted higher PFOA and PFOS levels are linked to specific kidney disease risks, with PFOA associated with hypertensive nephropathy and calculus of kidney.
- Open access
Machine learning and fugacity modeling reveal that river sediments intercept 26.6% of PFAS flux and altitude correlates with higher short-chain PFAS levels in the Third Pole-Tibetan Plateau.
- 2 cites
PFAS induce widespread hormetic responses across diverse ecological models, with biphasic dose-response patterns observed from bacteria to vertebrates.
- 3 cites
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