Mitoribosomal synthetic lethality is a vulnerability in MYC(N)-amplified neuroblastoma, with MYC activation sensitizing cells to mitochondrial ribosome inhibitors.
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Cancer therapeutics and mechanisms
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Topoisomerase I inhibitors induce a human microglial subtype with high CD74 and MHC expression that enhances amyloid beta uptake, reducing toxicity.
- Open access
A novel PCR-based method using a 1D-CNN ensemble achieves 100% accuracy in genotyping UGT1A1 rs3064744 alleles, overcoming platform variability in the Russian population.
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Journals this month
- bioRxiv6192
- medRxiv1716
- PNAS472
- Sci Adv398
- JAMA274
- Environ Res230
- BMJ200
- Nat Commun171
- Environ Pollution165
- Nature161
- NEJM146
- Science141
- Lancet132
- Cell Rep130
- Curr Biol108
- J Exp Bot108
- mBio107
- Plant Cell Environ107
Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
- Influenza Virus Research Studies3