Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

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Sexually dimorphic alternative splicing and its erosion following the loss of sex in stick insects
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.21.707240
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Haplotype-resolved genome assemblies and population resequencing reveal no evidence for genetic sex determination in the dioecious conifer Taxus baccata
bioRxiv · 16 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.27.708407
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Integrating sex as a biological variable into one's science.
Nature Methods · 14 Oct 2026 · Journal Article
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Population-scale Y chromosome assemblies reveal recurrent remodeling within constrained architectures
bioRxiv · 6 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.03.729890
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TangentXY: Improved copy-number estimation of sex chromosomes reveals features associated with aneuploidies in chromosomes X and Y across cancers
bioRxiv · 2 Oct 2026 · Preprint
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Complete Telomere-to-Telomere Assembly of the Y Chromosome in the Chinese Quartet
bioRxiv · 14 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.13.718326
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Reassessing the "sexy" X hypothesis reveals distinct cellular and disease signatures of X-linked genes in male sexual differentiation and reproduction
bioRxiv · 10 Sept 2026 · Preprint
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Estriol is a Stronger Transcriptional Activator than is either 17beta-Estradiol or Estrone of Hu-man and Elephant Shark Estrogen Receptor-alpha and Estrogen Receptor-beta transfected into COS-7 Cells
bioRxiv · 10 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.03.736429
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Trpv4 links environmental temperature to testicular differentiation in hermaphroditic ricefield eel.
eLife · 7 Sept 2026 · Journal Article
Trpv4 mediates environmental temperature effects on testicular differentiation in ricefield eel, with 50% of gonadal transformation linked to Trpv4 activity.
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Sexually antagonistic co-evolution at the molecular level: patterns of genetic co-variation predict phenotypic outcomes of mating interactions.
bioRxiv · 3 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.11.04.686516
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Human and mouse adrenal glands are characterized by species-specific steroidogenic states and tissue turnover.
Nature Genetics · 1 Sept 2026 · Journal Article
Human and mouse adrenal glands exhibit distinct steroidogenic states and tissue turnover patterns, with humans showing age- and sex-specific differences in adrenal cell functions.
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https://jclub.com.au/a/42711427
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Generation of induced pluripotent stem cell line NTUHi003-A from a patient with premature ovarian insufficiency.
Stem cell research · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42603520
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Modeling population control via tunable sex ratio distorter gene drives in Aedes aegypti, an arboviral vector with homomorphic sex chromosomes
bioRxiv · 28 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.05.736587
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Zebrafish Rif1 impacts zygotic genome activation, replication timing, and sex determination
bioRxiv · 28 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2022.10.21.512903
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