Acute Lymphoblastic Leukemia research

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Moved, week to 22 Oct 2026: 0
Papers in 60 days: 10

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Latest in Acute Lymphoblastic Leukemia research

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The NG2-ITGA4 axis regulates Rho GTPases and leukemic aggressiveness in KMT2A-r B-ALL and is targetable with natalizumab.
Blood · 15 Oct 2026 · Journal Article
The NG2-ITGA4 axis promotes leukemic aggressiveness in KMT2A-r B-ALL and can be targeted with natalizumab.
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Aquaporin-9 and aquaporin-10 but not aquaporin-3 confer susceptibility to dimethylarsinic acid genotoxicity in human cells
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.20.752519
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Developing cancer-control policies to address the cancer burden among young adults.
Nature Medicine · 24 Sept 2026 · Letter
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Venetoclax plus pediatric regimen in adolescents and adults with Ph-negative acute lymphoblastic leukemia.
Blood · 24 Sept 2026 · Clinical Trial, Phase II
Venetoclax combined with pediatric-inspired chemotherapy achieves a 91% remission rate and improves survival in adolescents and adults with newly diagnosed Ph-negative ALL.
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https://jclub.com.au/a/42166560
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Endothelial PERK restricts lymphoid regeneration by reducing DLL4-NOTCH3 signaling at the Pre-B niche.
Cell Reports · 22 Sept 2026 · Journal Article
Ablating endothelial PERK enhances DLL4-NOTCH3 signaling, boosting lymphoid regeneration by 50% after irradiation in hematopoietic recovery.
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A viral protein promotes host L-asparaginase activity and weakens the asparagine-induced resistance pathway for the benefit of virus infection.
Journal of Experimental Botany · 16 Sept 2026 · Journal Article
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https://jclub.com.au/a/42316991
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Inhibition of the atypical kinase WNK1 as a therapeutic strategy in TAL-related T-cell acute lymphoblastic leukemia.
Blood · 10 Sept 2026 · Journal Article
Inhibiting WNK1, an atypical kinase overexpressed in T-ALL, induces cell cycle arrest and disrupts mitosis, offering a promising therapeutic target with significant effects.
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Altered chromatin accessibility mediated by somatic cohesin mutations amplifies FLI1-Menin output to promote leukemogenesis
bioRxiv · 4 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.04.01.646632
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Effectiveness of Risankizumab After Ustekinumab Failure in Crohn's Disease: A Multicenter Retrospective Cohort Study.
Gastroenterology · 1 Sept 2026 · Journal Article
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A genomic and epigenomic lens into the biology of acute lymphoblastic leukaemia.
Nature Reviews Cancer · 1 Sept 2026 · Review
Genomic and epigenomic profiling reveal over 40 molecular subtypes of acute lymphoblastic leukemia, enhancing classification and informing treatment strategies.
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