A graded, revisable framework for ICU-acquired pneumonia diagnosis incorporates clinical, imaging, and microbial data, moving beyond binary pathogen detection.
- Open access
Moving in medRxiv, bioRxiv, Journal of bacteriology, mSystems, Nature Microbiology, Applied and environmental microbiology, Genome Medicine and Journal of hepatology.
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A graded, revisable framework for ICU-acquired pneumonia diagnosis incorporates clinical, imaging, and microbial data, moving beyond binary pathogen detection.
A stable 10-day in vitro lung microbiome model was established using four bacterial species, providing a controlled platform for respiratory microbiome research.
De novo monounsaturated fatty acid (MUFA) synthesis is essential for growth, stress tolerance, and cell viability in three major streptococcal pathogens.
Prevotella species are a common lung microbiome component linked to lung immune homeostasis and infection defense, with depletion associated with reduced survival in critically ill patients.
Pneumococcal population structure determines how air pollution influences invasive disease risk, with specific lineages and serotypes showing immediate effects.
A model incorporating negative frequency-dependent selection accurately predicts pneumococcal vaccine replacement dynamics, guiding surveillance strategies across diverse regions.
IL-1 family signalling is essential for mucosal defence against systemic Candida albicans infection, with its loss leading to dissemination and mortality in neutropenic conditions.
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Topics moving, week to 23 Oct 2026