Loss of Svep1 in mice causes increased disorganized distal airway tips and disrupted alveolar development, leading to lung hypoplasia and perinatal lethality.
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Neonatal Respiratory Health Research
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Inhaled ARO-RAGE siRNA safely reduces lung RAGE levels and pulmonary inflammation in humans, demonstrating effective target engagement in a first-in-human trial.
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Topics moving, week to 22 Oct 2026
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