Sarcoma Diagnosis and Treatment
Moving in Cancer Research, medRxiv, bioRxiv, Cancer Discovery and Cell Reports.
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Latest in Sarcoma Diagnosis and Treatment
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High-risk rhabdomyosarcomas exhibit a shared convergent cell state with neural features, regardless of FOXO1 fusion status.
- Open access
Expanded DNA methylation-based sarcoma classifier achieves 98% accuracy across 116 tumor sub-classes, significantly enhancing diagnostic precision for mesenchymal tumors.
- Open access
- 3 cites
BRD9 degradation enhances GBAF chromatin remodeling activity in synovial sarcoma, undermining therapeutic efforts with minimal impact on tumor proliferation.
- Open access
A pediatric patient-derived xenograft (PDX) program created 388 models across 40+ diagnoses, including ultra-rare tumors, enabling detailed cancer biology and therapy studies.
IL1RAP antibody-drug conjugates effectively target primary and metastatic tumors in multiple oncofusion-driven cancers, causing tumor regression and reducing metastasis.
- Open access
- 1 cites
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