Antibiotic Resistance in Bacteria

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Metagenomics for antimicrobial resistance: from resistome surveillance to mechanistic inference.
Journal of bacteriology · 20 Aug 2026 · Review
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Control of cell division by an Acinetobacter baumannii protein with a nucleotidyl cyclase-like domain
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.03.716176
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Wildlife-associated ecosystems in Algeria harbor internationally distributed ESBL-producing clones and plasmids, including a CTX-M-15 Klebsiella pneumoniae ST17 lineage associated with a conserved IncFIB(K) resistance plasmid.
Applied and environmental microbiology · 21 Oct 2026 · Journal Article
Wildlife-associated ecosystems in Algeria harbor internationally distributed ESBL-producing Klebsiella pneumoniae ST17 and other high-risk Enterobacterales lineages with conserved resistance plasmids.
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https://jclub.com.au/a/42904662
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A One Health perspective on mobile genetic elements and associated antibiotic resistance genes in non-human A. baumannii.
Applied and environmental microbiology · 21 Oct 2026 · Review
Mobile genetic elements in non-human A. baumannii are linked to antimicrobial resistance and suggest circulation between human and non-human populations.
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https://jclub.com.au/a/42770716
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Differential impacts of early, extended-spectrum, and last-resort β-lactams on manure-derived microbiomes and resistomes in an in vitro model.
mSystems · 21 Oct 2026 · Journal Article
Extended-spectrum and last-resort β-lactams cause more pronounced shifts in manure-derived microbiomes and resistomes than ampicillin in an in vitro model.
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Genomic divergence and phenotypic heterogeneity of Legionella longbeachae reveal a putative novel proinflammatory serogroup with genome reduction and mobilome expansion.
Applied and environmental microbiology · 21 Oct 2026 · Journal Article
A novel Legionella longbeachae serogroup 3 exhibits genome reduction to 4.01 Mb, lacks plasmids, and induces increased host cell death and proinflammatory cytokine expression.
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Antidepressant desvenlafaxine identified in wastewater promotes transformation and antibiotic resistance risk in Acinetobacter baylyi ADP1 via metabolic adaptations.
Applied and environmental microbiology · 21 Oct 2026 · Journal Article
Desvenlafaxine significantly increases bacterial transformation frequency in Acinetobacter baylyi ADP1 at 10 and 50 mg/L, promoting potential antibiotic resistance spread.
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High-risk antimicrobial resistance genomic traits in multidrug-resistant Salmonella across China's food chain: projections to 2050.
Nature Communications · 20 Oct 2026 · Journal Article
Eighty-four high-risk antimicrobial resistance traits in MDR Salmonella are projected to increase by 2050, driven by socioeconomic, climate, and healthcare factors in China.
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Evolution of multidrug-resistant IncC plasmids in the seventh pandemic Vibrio cholerae O1 El Tor lineage between 1979 and 2024
bioRxiv · 16 Oct 2026 · Preprint
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Mechanistic insights into stereoselective effects of S-naproxen and R-naproxen on conjugative transfer of antibiotic resistance genes.
Environmental pollution · 15 Oct 2026 · Journal Article
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A citywide metagenomic analysis reveals surface-specific microbiome and resistome patterns in outdoor urban environments across Liverpool, UK.
bioRxiv · 8 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.18.706585
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Bacterial Mercury Resistance Reveals a Robust Species-Structured Human Antimicrobial Mobilome
bioRxiv · 7 Oct 2026 · Preprint
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PanRes: A database of latent and acquired antimicrobial resistance allowing 3D-based protein homology search
bioRxiv · 6 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.22.733705
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Selected plasma-associated molecular species remodel the ABCB1 linker with effects retained under structure-derived tethering
bioRxiv · 4 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.08.13.670033
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Structure-Informed Stress-Testing of the Standard Numbering Scheme for Class B β-Lactamases Using AlphaFold2
bioRxiv · 3 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.01.756119
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Global dynamics of antibiotic resistance: a modeling study of the spread of endemic and emerging resistance in E. coli
medRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.25.25335519
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Positive control of the integrative and conjugative element Tn916 and its limited gene expression in transconjugants
bioRxiv · 2 Oct 2026 · Preprint
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Klebsiella genus as driver of human disease: from infections to non-communicable disorders.
Nature Reviews Microbiology · 1 Oct 2026 · Review
Klebsiella spp. are linked to both acute infections and non-communicable disorders, with evidence associating them with chronic inflammatory, metabolic disorders, and cancer.
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The role of intracellular ROS in the development of antimicrobial resistance:A convergent mediator linking mutations and horizontal gene transfer.
Environmental pollution · 1 Oct 2026 · Review
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Antimicrobial stewardship in LMICs: from paper promises to purpose-driven people.
Nature Reviews Microbiology · 1 Oct 2026 · Journal Article
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Hydrological seasonality shapes antibiotic resistome assembly and dissemination risk in a reclaimed-water-fed urban river.
Environmental research · 1 Oct 2026 · Journal Article
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Multi-scale analysis of patterns, risks, and mechanisms of edaphic antibiotic resistance genes on the Qinghai-Tibet Plateau: Integrating regional and national perspectives.
Environmental pollution · 1 Oct 2026 · Journal Article
Soil antibiotic resistance genes (ARGs) are significantly more abundant, diverse, and transferable in anthropogenically disturbed soils on the Qinghai-Tibet Plateau, with yak feces as a major source.
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https://jclub.com.au/a/42385824
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Building-block synthesis as a determinant of antibiotic persistence.
Nature Communications · 28 Sept 2026 · Journal Article
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https://jclub.com.au/a/42881196
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Diagnosing antimicrobial stewardship needs in a pluralistic health system in India: Why Local Evidence Must Guide Implementation
medRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.26363886
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Novel Synthetic Polymyxin Variants Inspired by Newly Uncovered Natural Sequences Explored as Potential Antibiotics
bioRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.25.754415
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Spatiotemporal dynamics and stability of multi-kingdom microbial communities in hospital sinks acting as persistent pathogen reservoirs
bioRxiv · 26 Sept 2026 · Preprint
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Rapid classification of β-lactamase activity through AI-based structure prediction and electric field analysis
bioRxiv · 25 Sept 2026 · Preprint
AI-based structure prediction and electric field analysis enable rapid classification of β-lactamase activity with an R2 of 0.8, significantly speeding up resistance assessment.
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https://jclub.com.au/a/10.64898/2026.09.23.753769
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WITHDRAWN: Blocking IF3N delays bacterial translation initiation
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.03.14.643242
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Genetic Relationships of Third-Generation Cephem Resistant Escherichia coli in Humans, Dogs and Cattle using a Novel Clonotyping Assay
medRxiv · 25 Sept 2026 · Preprint
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Fine-scale structural diversification among closely related Legionella pneumophila isolates from a bath-associated environmental reservoir.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
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Klebsiella pneumoniae from fuchka: insights into the genetic diversity, virulence, and antibiogram profile.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
Nearly half (46.7%) of street food samples in Bangladesh contained Klebsiella pneumoniae, with 37.5% showing multidrug resistance and high virulence gene prevalence.
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