Loss of p75 NTR causes hypoplasia, reduced chondrocyte number, and accelerated degeneration in the mandibular condylar cartilage.
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Loss of p75 NTR causes hypoplasia, reduced chondrocyte number, and accelerated degeneration in the mandibular condylar cartilage.
Spatial transcriptomics uncovers a conserved osteogenic core-halo architecture with disrupted cell interactions in sclerotic subchondral bone of osteoarthritis patients.
Hypertension exacerbates osteoarthritis, suggesting it may serve as a therapeutic target for managing both conditions.
Gene-regulatory changes in over 15,000 loci drove extensive remodeling of the human skeletal extracellular matrix, including a three-to-fourfold reduction in joint GAG content.
Increased homozygosity significantly raises ACL rupture risk in Rottweilers but not in Labrador Retrievers, highlighting breed-specific genetic influences.
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Topics moving, week to 23 Oct 2026