Coordination of quorum sensing with T3SS and T6SS: Bacterial strategies for combating fungal pathogens.

Quorum sensing regulates bacterial secretion systems that deliver antifungal effectors, with T6SS disrupting fungal cell integrity and T3SS mediating mutualistic and antagonistic interactions.

• Why it matters: Bacterial-fungal interactions are vital for ecosystem balance, yet the mechanisms controlling these interactions and their potential for controlling fungal pathogens are not fully understood.
• What they did: The review examines the antifungal roles of T6SS and T3SS and highlights quorum sensing as a key regulatory framework influencing microbial community dynamics.
• The result: Understanding these bacterial strategies may enable the development of innovative approaches to combat fungal pathogens, benefiting agriculture and environmental management.