Clinical management, antifungal susceptibility, and predictors of 28-day mortality in Candidozyma auris candidemia: A single-center cohort study.

28-day mortality in Candida auris candidemia patients was 41.1%, with higher Charlson Comorbidity Index and SOFA scores independently linked to death.

• Why it matters: Understanding factors associated with mortality in Candida auris infections is crucial due to high mortality and limited treatment options, especially in critically ill patients.
• What they did: A retrospective cohort of 108 adult patients at a tertiary care center was analyzed for clinical management, microbiological outcomes, antifungal susceptibility, and mortality predictors, using multivariable analysis.
• The result: Baseline comorbidity burden and organ dysfunction were associated with increased mortality; high resistance rates to fluconazole and multidrug resistance highlight the importance of local resistance monitoring and early risk recognition.