The global prevalence of disorders of gut-brain interaction remains consistent at around 41% using Rome V criteria, confirming high worldwide burden.
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Gastroesophageal reflux and treatments
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Surgical and endoscopic therapies, including radiofrequency, plication, and mucosal resection, offer diverse options for treating GERD patients.
Achalasia is strongly linked to esophageal squamous cell carcinoma, with an odds ratio of 9.46, but its connection to adenocarcinoma is weaker and largely explained by GERD.
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