Reproductive tract infections research

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The Chlamydia trachomatis effector CT226 directly engages LRRFIP1 to recruit a multiprotein complex that limits inclusion size and progeny production.
mBio · 14 Oct 2026 · Journal Article
CT226 effector protein of Chlamydia trachomatis recruits a host multiprotein complex via direct binding, modulating inclusion size and bacterial progeny production.
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https://jclub.com.au/a/42752221
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Modulating the gut-reproductive tract axis: microbial influence on gynaecological cancer pathogenesis and treatment.
Gut · 7 Oct 2026 · Review
Distinct alterations in gut microbiota, including reduced diversity and dysbiosis-associated taxa, are linked to ovarian, endometrial, and cervical cancers in patients.
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Gastroenterology · 1 Oct 2026 · Letter
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Sphingolipids associate with the chlamydial nucleoid and mark developmental transitions in Chlamydia trachomatis.
Nature Communications · 30 Sept 2026 · Journal Article
Sphingolipids localize within Chlamydia trachomatis nucleoids and mark early developmental transitions, with sphingomyelin linked to DNA condensation in elementary bodies.
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https://jclub.com.au/a/42816552
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Vaginal epithelial estrogen receptor α regulates vaginal pH without detectable changes in glycogen content or microbial diversity in mice
bioRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.29.685365
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Benchmarking virus identification tools on vaginal metagenomes
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.753817
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Characterization of vaginal lactobacilli from South African women toward the development of a biotherapeutic to optimize the vaginal microbiome.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
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https://jclub.com.au/a/42627216
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Utilizing natural competence to genetically manipulate Lactobacillus iners.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
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Species and strain sharing in the vaginal microbiome of mothers and their adult daughters.
Cell Reports · 22 Sept 2026 · Journal Article
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https://jclub.com.au/a/42709542
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Mother-infant sharing of gut and vaginal microbes at the species and strain level.
Cell Reports · 22 Sept 2026 · Journal Article
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https://jclub.com.au/a/42684889
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The role of extracellular DNA in Neisseria biofilms.
Journal of bacteriology · 17 Sept 2026 · Review
Extracellular DNA is essential for the formation, structure, and stability of Neisseria biofilms, with eDNA contributing to biofilm development in pathogenic and commensal species.
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Human Papillomavirus Screening and Self-Collected Vaginal Samples.
JAMA · 15 Sept 2026 · Journal Article
2025 guidelines recommend HPV screening and self-collected vaginal samples as effective tools for cervical cancer detection.
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Constructing microbiome co-occurrence networks with confidence: A conditional, nonparametric, inference-based approach
bioRxiv · 1 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.27.747483
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Robust taxonomic classification in gut and vaginal microbiomes demonstrated through benchmarking with age-specific synthetic communities
bioRxiv · 29 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.06.736764
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A new core-genome MLST approach for Chlamydia trachomatis genomic surveillance and research.
Nature Communications · 27 Aug 2026 · Journal Article
A new core-genome MLST system for Chlamydia trachomatis accurately recapitulates major lineages and enables global phylogenomic tracking with 846 loci.
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