Advancing the adoption of RNA interference-based biopesticides.

RNA interference-based biopesticides have transitioned from proof of concept to practical use with the first products targeting Colorado potato beetle and varroa mite.

• Why it matters: This work addresses the need for targeted, safer pest control options amid environmental concerns, pesticide resistance, and regulatory restrictions on conventional chemicals.
• What they did: Researchers highlight advancements in bioinformatics, risk assessment, and delivery systems that support the adoption of RNAi biopesticides, considering factors like efficacy, regulation, and public perception.
• The result: These developments position RNAi biopesticides as a viable market alternative, though widespread adoption depends on overcoming regulatory fragmentation and gaining social license.