Antifungal drug resistance in Candida auris: molecular mechanisms and emerging therapeutic approaches.

Candida auris exhibits frequent multidrug resistance, complicating treatment and enabling global healthcare outbreaks.

• Why it matters: Understanding the molecular mechanisms of antifungal resistance in C. auris is crucial for improving clinical management and developing effective therapies for invasive infections.
• What they did: The review summarizes current knowledge of C. auris, details mechanisms of clinical resistance, and highlights recent advances in antifungal drug discovery and therapeutic strategies.
• The result: Insights into resistance mechanisms and new therapeutic approaches may help control outbreaks and improve treatment outcomes for C. auris infections.