Leveraging traveller genomics for LMIC diarrhoeal disease management.

Traveller-derived genomic data reveal distinct geographical patterns of diarrhoeal pathogens and antimicrobial resistance in LMICs, offering potential to enhance local surveillance.

• Why it matters: Effective diarrhoeal disease management in LMICs is limited by poor microbiological capacity and challenges in genomic surveillance, risking inadequate treatment and control measures.
• What they did: The authors review the use of large volumes of pathogen genomes from travellers returning from LMICs in high-income countries, emphasizing their potential to inform geographically specific antimicrobial treatment strategies.
• The result: Integrating traveller genomics into LMIC public health systems could improve disease surveillance and antimicrobial stewardship, though ethical, practical, and governance issues must be addressed.